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Working Group 1 : Inter-individual variation in bioavailability

Main Tasks : 

  • Indentify the main factors involved in between subject variations in bioavailability of plant food bioactives
  • Improve methods and Tools to asses individual's exposure to plant food bioactives

Expected concrete outcomes :

  • Inventory of factors substantially affecting absorption and metabolism for each family of bioactives
  • New paradigm and related methods to stratify individuals into defined "metabotypes"
  • List of candidate genes variants, gut microbiota species and activities associated with the identified metabotypes
  • Consensus on the usefulness of new approaches (metabolomics) to asses individual's exposure

Leadership :

Tom VdW 5


Prof. Tom Van de WIELE

Univ. Ghent - Belgium


Co leader 1


Univ Agricultural Science - Sweden

Co leader 2

Dr. Claudine MANACH

INRA - France